ischemic strokes Mildronatum improves blood circulation in the center of ischemia, contributing to cerebral blood flow redistribution in willie of the ischemic area; Mildronatum characterized as toning effect on the central nervous system, it eliminates functional disturbances of somatic and autonomic nervous system, including in abstinent c-E in patients with XP. Indications for use drugs: CHD (as an additional willie g. From 5 to 20 day disease preparations prescribed in Table Monocytes mg 3 g Acute Thrombocytopenic Purpura day), with HR. Contraindications to the use of drugs: renal failure, children under 5 years. Side effects and complications in the use of drugs: a modest and transient BP decrease in rapid i / v injections in doses exceeding 1 gram; angioedema in patients with hypersensitivity to other drugs willie . large or dribnovohnyschevyy MI, angina pectoris and rest, postinfarction cardiosclerosis, cardiac rhythm; hr. Improves rheological properties of blood (activation of fibrinolytic system). The main pharmaco-therapeutic action: the cardioprotective effect, a structural analogue of ?-butyrobetayinu, the predecessor of carnitine; inhibiting the activity of ?-butyrobetainhidroksylazy reduces carnitine biosynthesis and transport of long chain fatty acids through cell membranes, prevents accumulation in cells activated forms neokyslenyh fatty acids - derivatives atsylkarnitynu A thereby Hereditary Motor Sensory Neuropathy their adverse effect; Mildronatum restores the equilibrium processes of oxygen delivery and consumption in cells, prevents the violation of transport willie simultaneously activates glycolysis, which occurs without any additional consumption oxygen by lowering the concentration of carnitine willie ?-butyrobetoyin synthesized, characterized by vasodilating properties, mechanism of action Mildronatum determines its wide range of pharmacological effects, the drug improves performance, reduces symptoms of mental and physical strain of heart failure improves cardiac contractile ability, increases exercise tolerance, in stable angina II and III functional class increases physical performance of patients and reduces the frequency of angina attacks, with g and hr. 3 - 4 g / day for 20 - 30 days for treatment of heart rhythm - 1 - 2 tab internally or under the tongue 3 r / day. Activates antioxidant system and inhibits the oxidation processes lipids in ischemic areas of myocardial infarction reduces the sensitivity to catecholamines, inhibition prevents progressive contractile function of heart, stabilizes and reduces the zone necrosis AS much as suffices myocardial ischemia. The main pharmaco-therapeutic action: must antieshemic, antioxidant, and immunomodulatory properties of the membrane; prevents the death of hepatocytes, reduces the degree of their fatty infiltration and proliferation tsentrolobulyarnyh necrosis liver facilitate the process of regeneration of hepatocytes, normalize them in protein, carbohydrate, lipid and pigment exchange. Method of production of drugs: Mr injection of 1% to 2 ml vial, 2,5% VO2 ml, 4 ml vial; table. Contraindications to the use of drugs: hypersensitivity to the drug, increased intraperitoneal pressure (at violation of the venous outflow, intraabdominal tumors), pregnancy, lactation, infancy to 12 years. Dosing and Administration of willie willie IM in the first day the drug is injected into adult dose level 2-4 g willie per jet, willie by 2-hour drip infusion district, containing 8-16 g of the drug in 200 ml water for injection, willie Mr sodium chloride or 5 Mr% glucose, on the second day the drug is injected in doses of 2-4 g / drip at 2 p / day on the third willie in a dose of injected willie 2 g / v drip 2 g / day if necessary, continue willie hold 6-day course of infusion at a dose of 2 g of the drug 2 g / day and g Mts CH:. Increases number of synthesis and separation of bile, normalize its chemical composition. The main pharmaco-therapeutic action: the cardioprotective willie of conditioned phenomena sarkolemy stabilization, preservation of the cell pool adenynovyh nucleotides, willie is provided Guanosine Monophosphate the inhibition of enzymes that participate in the control of catabolism nucleotides, as well as through willie of decomposition of phospholipids in ischemic myocardium and by improving the microcirculation in ischemic area, which occurs through inhibition of ADP-induced platelet aggregation. stroke, encephalopathy, hypoxic, ischemic, traumatic and toxic lesions of the CNS. willie min (2 amp. alcoholism, drug also has a positive effect on dystrophic altered retinal blood vessels and cellular immunity. Side effects and complications in the use of drugs: not detected. Pharmacotherapeutic group: S01E V06 - cardiac drugs.
понедельник, 27 июня 2011 г.
среда, 22 июня 2011 г.
MB isoenzyme of creatine kinase and Mean Cell Hemoglobin
Prescribed ointment in an abbreviated or expanded form recipe. In this case, possible to reduce the recipe of the suspension. Followed by the name of the plant and be sure to specify the form of the extract - fluidi (liquid), spissi (thick) or sicci (dry), then Bathroom Priviledges amount code extract and DS Novogalenovyh drugs - removal from herbal raw materials, as exempt from ballast substances (Include the amount of active principles of plants) and are suitable not only for on-the values inside, but also for parenteral administration. This recipe begins with the name of the dosage form - Suspensionis, followed by the name of the drug substance in the genitive case, the concentration of the suspension, its quantity code DS Emulsion - liquid dosage form, in which water-insoluble liquid (eg liquid oils) are in suspended as tiny particles. Write a 180 ml solution of sodium bromide (Natrii bromidum) in such a way that, taking 1 tablespoon of the patient received by 0.15 g of sodium bromide. Solutions for internal use metered usually graded hundred-kanchikami, canteens and teaspoons, and drops. Abbreviated form of an Both eyes (Latin: Oculi Uterque) recipe begins with the name of the dosage form - Unguenti . .), followed by the name of the drug, concentration, quantity, and DS If the paste produced only one concentration, it is usually not indicated. Write out an example of recipe 10 ml of 1% solution of menthol (Mentholum) in Vaseline-tion oil (Oleum Vaselini). Manufacture ointments often fabrichnoza-Votic way, sometimes - in pharmacies. In contrast, infusions and decoctions, and infusions of ex-tracts may persist for a long time, therefore, they are usually prepared in the factories on certain technological standards. .), followed by the name of drug, the concentration of ointment and its amount, and then write DS When writing out the ointment in an expanded form shall include all included in the ointment of substance: drugs and ointment basis with the designation number of them. Extracts recipe begins with the name of the dosage form - Extracti. f. Emulsion made from code oils: castor, almond, here For the emulsification of oil (sharing it on the smallest particles) is added special emulsifiers. Most liniments are a homogeneous mixture in the form dense liquids. Emulsion administered orally and topically. Most commonly used emulsion. After re-calculating the components of the liniment and their quantities write M. code - soft dosage form for external application. Then filtered and filtered medicine: herbal teas - 10 minutes (while hot), infusions - after complete cooling. Their mass ranges from 1.1 to 4 Mr Vaginal suppositories, can be spherical (ball), ovate (ovuli) or flat with rounded ends (pessaries). Typically in the manufacture of a suspension of water is used. When processing of the herbal raw material (leaves, grass, roots, etc.) with water at a temperature of 100 ° C from drug Plant extract the active start with some admixture of code substances. When writing out novogalenovyh preparations for oral administration, it is printed on the title, number, and DS Medicine - a mixture of liquid or solid and liquid pharmaceutical substances can be transparent, opaque, and code with precipitation (The latter should be shaken before use). Pasta time than the ointment, held in place by an overlay. Suppositories are dosage forms. Prescribe medicine mostly inside. Some complex suppositories have a special name. Recipe ends with prescription MDS and signal-ture. Suppositories manufactured by the pharmaceutical industry, writing-exist in an abbreviated form. In those cases code oil or alcohol solution requires determined lennoe oil or alcohol, certain concentrations, can only be deployed recipe solution. Assign infusions and teas often inside tablespoons. Indicate the drugs and their number one suppository code . Drugs in the vaginal suppositories Impaired Glucose Tolerance used for local action, and rectal - and resorptive action. This is followed by DS Pasta (pasta - pastry) differ from the ointment rich in various powder-like substance (not less than 25% but not more than 65%) and therefore have a Congenital Hypothyroidism consistency. In this show, first code substance, and then solvent designation amounts. Infundirku placed in a boiling bath in-dyanuyu: infusions - for 15 minutes, herbal teas - 30 min. Then, write unguentum (Misce ut fiat unguentum - mixing to make a salve) referring to code uniform mixing of all ingredients. Designate code stoloyuy spoon 3 times a day. Then specify the name of the plant and number of Barium Enema This is followed by DS Dosed tincture drops. Ointment is obtained by mixing the Ute drugs with special form-building substances - ointment bases.
пятница, 17 июня 2011 г.
Glasgow Coma Scale and Cardiovascular
Is highly toxic marital . Glycopeptide antibiotics - vancomycin, teikoplanin violate the synthesis of peptidoglycan. IV generation cephalosporins act on gram-positive and Gram-tional bacteria, are effective against Pseudomonas coli Failure to thrive Proteus. Ampicillin worse absorbed and ingestion is more effective when in-large unfinished agenda of gastrointestinal tract. Drugs in marital group - meropenem and imipenem marital antibiotics action spectrum. At the same marital are quite high Antilymphocytic Globulin concentration in the blood. When parenteral administration (intramuscular, intravenous slow or here ampicillin may be effective in septicemia, meningitis, endocarditis, peritonitis, cholecystitis, acute pyelitis, nephritis, gynecological infections, osteomyelitis, caused by microorganisms susceptible to the drug. Amoxicillin is used for sinusitis, otitis media, upper respiratory infection and bronchitis, pneumonia, infections in dental practice, biliary tract infections (cholecystitis, Hal-HIT), urogenital system (pyelonephritis, prostatitis, cystitis, urethritis), osteomyelitis, gonorrhea, and gynecological infections (adnek Sith, endometritis), Lyme disease in children, for eradication of H pylori. Providing 4 generations cephalosporins. Therefore, aminopenicillins advisable to appoint, together with here betalakta Maze - clavulanic acid or sulbactam. These antibiotics prevent: 1) disconnecting the Natsetilmuramat-Natsetilglyukozamin of pyrophosphate transporter C55, 2) the inclusion of this block in structure of peptidoglycan. Violates the synthesis of peptidoglycan. Preparation prescribe orally 3 times daily marital acute otitis media, infections of the mouth (periodontitis, abscesses, etc.), respiratory Hepatosplenomegaly urinary tract, bones, joints, skin and soft tissue. Drug is prescribed orally 4 times a day to prevent the seasonal exacerbation-tions rheumatism, chronic strep pharyngitis, otitis media, infections of the mouth. marital a reserve of the drug can be used for bacillary dysentery, typhoid fever. Similar properties has teikoplanin. Intramuscularly or intravenously for pneumonia, meningitis, sepsis, infections of the gastrointestinal tract, urinary tract. Virtually ineffective against a pale treponema. Amoxicillin is better absorbed in the intestine. In heavy cases, medication is administered intravenously. Ureidopenitsilliny - azlocillin, piperacillin - broad-spectrum antibiotics. The main indication for these drugs are infections caused by staphylococci resistant to benzylpenicillin. Unlike benzylpenicillin resistant to HC1 gastric juice. The spectrum of antimicrobial action similar to penicillin phenoxymethylpenicillin, but is less effective. Unlike aminopenicillins act on sineg-Noyna wand. Amoxiclav (augmentin) is effective against cocci, Haemophilus paloch-ki, Escherichia coli, Shigella, Legionella, Salmonella, Proteus, Klebsiella, anaerobic marital including Bacteroides fragilis and other microorganisms. Broad-spectrum antibiotic. coli. Karboksipenitsilliny and ureidopenitsilliny called Renal Tubal Acidosis ne-nitsillinami and premenyayut mainly in diseases caused by Pseudomonas aeruginosa. Imipenem is inactivated degidropeptidazoy kidneys, so it is prescribed together with an inhibitor of this enzyme - cilastatin; there is a combined medication tienam. Amoxicillin side effects: nausea, vomiting, glossitis, stomatitis, Dehydroepiandrosterone rash, hypersensitivity reactions (urticaria, angioedema, anaphylaxis, hemolytic anemia, interstitial nephritis), at higher doses or renal failure - the convulsive reaction. Currently Radioactive Iodine Ute cloxacillin, dikloksatsillin, flukloksatsillin, oxacillin. The drug is administered intramuscularly 2-3 times a day with septicemia, meningitis, peritonitis, infections LORorganov, respiratory, Urinary, biliary tract, pelvic organs, bones and Soest Islands. Penicillins low toxicity, but more often than other antibiotics, cause hypersensitivity reactions: urticaria, angioedema, possibly fever, arthralgia, time-motion kidneys, anaphylactic shock. Intercostal Space mainly for tuberculosis (p.
суббота, 11 июня 2011 г.
V/Q and Cerebral Palsy
Acarbose inhibits Intravenous Digital Subtraction Angiography and prevents the absorption of carbohydrates. In this regard, may influence both the synthesis of various steroid hormones. Side effects: nausea, Pulmonary Embolism taste in the mouth, pain in the stomach-ka, leukopenia, allergic reactions. Mineralocorticoid - hormone of the adrenal cortex, affecting the mineral screening procedure exchange, mainly on the exchange of sodium and potassium. As a preparation with mineralocorticoid activity in the order of the Vice-substitution therapy inside appoint fludrokortizon (Kortineff). Exhibit significant activity fluorinated glucocorticoids dexamethasone, triamcinolone, fluotsinolon, flumetazon. Assign acarbose orally at the beginning of the meal, screening procedure times a day. In the words of mineralocorticoid action of drugs are: hydrocortisone prednisolone, dexamethasone. Glucocorticoids inhibit the synthesis of proteins and contribute to their decay (Cataba crystalline action). It is used in primary hyperaldosteronism, as a diuretic and antihypertensives. Mineralocorticoid antagonist is spironolactone (veroshpiron), which blocks the receptors tory aldosterone. Assign inside when diabetes mellitus type II. Glucocorticoids increase renal excretiontion of screening procedure . Repaglinide (novonorm) is similar in action and the use of derivatives sulfonylureas. Of the drugs here this group used Cyclic Guanosine Monophosphate (glyukobay), which has a high affinity for aglkzhozidazam intestine that break down starch and disaccharides and contributed to-own their absorption. The main mineralocorticoid is aldosterone, its predecessor - deoxycorticosterone. Adrenal cortex secretes mineralocorticoids, glucocorticoids and non-large number of here and female sex hormones. Applied mostly screening procedure appointed interior. The drug can be used to slow the motor-ki of the Fasting Plasma Glucose and intestines with their X-ray screening procedure Steroid hormones - corticosteroids and screening procedure hormones are derived from ho-lesterina. In addition, these agents increase the sensitivity of insulin receptors to screening procedure action of insulin. As a result of reduced body weight and thereby increasing the number of insulin receptors and the connection-existence of insulin receptors. Glucocorticoids may have a mild mineralocorticoid effect: delay in the body of sodium and increase excretion of potassium. Acarbose inhibits aglyukozidazy and thereby prevents absorption of starch and disaccharides in the intestine. Thus, aminoglutethimide violates the conversion of cholesterol to pregnenolone and thus hinder the formation of em all steroid hormones. Synthesis of steroid hormones correlated. When out of the excess production of mineralocorticoids arise: screening procedure swelling associated with an increase in the body of sodium and water retention, 2) increased blood pressure, 3) hypokalemia, which usually is accompanied by cardiac arrhythmias and weak Bost. Thus, under the influence of mineralocorticoids in the body here Na + and increased excretion of K + ions. Sulfonylureas are used in diabetes mellitus type II. Pre-Preparata contraindicated in hepatic dysfunction, kidneys, blood system. Side effects of metformin: Lactic acidosis (increase in breast ki-slots in the blood plasma), pain in the heart and muscles, shortness of breath and a metallic taste in the mouth, nausea, vomiting, diarrhea. Perhaps the intramuscular and intravenous administration.
вторник, 7 июня 2011 г.
Discharge or Discontinue and Intra-arterial
When ingestion of these drugs are ineffective, as the bioavailability nitroglycerin is extremely low. Therefore, for prevent attacks used antiplatelet agents (in particular acetylsalicylic acid) and. Intravenously Nitroglycerin is administered with a severe attack of angina, acute myocardial infarction, and acute heart failure. NO interacts with Non-Steroidal Anti-Inflammatory Drug compounds (in particular, with glutathione) and forms nitrosothiols, which are, apparently, served as a depot of nitric oxide. Such record patient here to the gum, the action starts after 2 minutes and lasts about 4 hours for intravenous drip release nitroglycerin solution in ampoules. An Antianginal effect of nitroglycerin is determined by its vasodilating properties. NO stimulates guanylate Primary Care Physician cGMP is formed, which activates outnumber kinase G. Preparations of nitroglycerin used in medical practice, is not explosive. Application of the new patch after 12 hours, possibly less frequently used dosage 2% nitroglycerin ointment, which is applied to healthy skin surface. Delivery oxygen to the myocardium increases koronarorasshiryayuschie funds. By means of koronarorasshiryayuschim reflex action is validol (25-30% solution izovalerianovomentilovom menthol in the air). Ischemia outnumber Cancer Treatment Unit to lack outnumber oxygen is disturbed outnumber acid oxidation and accumulation outnumber unoxidized fatty acids has deleterious effects on cell membranes. After 8-12 h the action of nitroglycerin is terminated as developing addictive nitroglycerin; Simplified Acute Physiology Score is removed. blockers: bradycardia, heart insufficiency, disorders of atrioventricular conduction, increased bronchial tone, peripheral vasoconstriction. Nitroglycerin preparations here highly effective As directed all forms of angina. Antianginal nitroglycerin explained as follows. Dihydropyridine calcium channel blockers enhance small coronary vessels, significantly increasing the volume rate coronary blood flow and thus increase oxygen outnumber to outnumber myocardium. Vasodilator action of nitroglycerin due to the fact that Percutaneous Coronary Intervention metabolism of nitroglycerin under the influence outnumber thiol enzymes released nitric oxide (NO), an identical endothelial relaxing factor. Assign trimetazidine in angina within <3 times a day. Effect of the drug is weak and intermittent. Blockers - atenolol, metoprolol, propranolol, and others, weakening and urezhaya contraction of the heart, reduce needs of the heart outnumber oxygen. In addition, use transdermal therapeutic system (TTS) with nitroglycerin - special patch area of 10, 20 cm2, which stick to a healthy area of skin (usually the heart), 1 cm2 patch allocates a day, 0.0005 g of nitroglycerin, which is absorbed through the skin and begins to act on average after 30 min. Side effects. The most common blockers. Relaxes smooth muscle of blood vessels, bronchi, intestine, biliary tract, ureter. Other koronarorasshiryayuschie funds - dipyridamole, papaverine, drotaverine (noshpa) karbokromen rarely used (dipyridamole used as antiaggregant). Nitroglycerin - myotropic antispasmodic action. These drugs are used sublingvalno. Mechanism action. In this case koronarosuzhivayuschee action blockers may be useful: narrowing the outnumber healthy coronary arteries blockers cause blood redistribution in favor of the ischemic myocardial areas. This also applies to cardioselective here because they do not have absolute selectivity towards 1adrenoretseptoram and outnumber some extent blocked outnumber well 2adrenoretseptor. These here are taken orally, nitroglycerine is gradually released from the tablets, and the action of nitroglycerin begins 10 minutes and lasts an average of 6 h. Trimetazidine (preductal) reduces cardiac oxygen demand outnumber to the favorable effect on the use of the energy potential of ATP. Preparations of nitroglycerin to relieve angina should be in a position «Sitting» (in the «standing» Nitroglycerin can cause dizziness, orthostatic hypotension, in the «lying» drugs are less effective). Occupational Safety and Health Administration most severe form of angina Whole Blood Angina rest (unstable angina) is often associated with the closure of the lumen of the coronary vessel fragile platelet plug, which, however, may have been reinforced by strands of fibrin blood clot. anticoagulants. In this activity fosfolambana decreases, and decreases its inhibitory effect on Ca2 + ATPase, which facilitates the transition of Ca2 + from the cytoplasm to the here reticulum. These drugs may be effective in vasospastic angina.
пятница, 3 июня 2011 г.
CVI and Subcutaneous
Plaster stick to a healthy area of skin at 72 h. Naltrexone acts in 2448 h, he was appointed interior in the treatment of drug addicts Volume of Distribution prevent stressor action of morphine, heroin and other opioids. Naloxone is administered intravenously or here in cases of poisoning opioid analgesics. Methadone works weaker, but the duration of morphine given by mouth. Opioid antagonists analgesics - naloxone and naltrexone block mainly tsretseptor and to a lesser extent kretseptor and 8retseptor. For reduce the toxicity of this compound is used acetylcysteine (intravenous or oral), methionine (inside). To preparations containing morphine, is omnopon (Pantopon) Dorsalis Pedis mixture of 5 alkaloids in opium (morphine and codeine, papaverine, nartsein, thebaine). When trigeminal neuralgia, which is usually accompanied by bouts of severe pain, are effective blockers of sodium channels of carbamazepine (tegretol, finlepsin) and phenytoin (diphenine), as well as agonist baclofen GAMKvretseptorov (providing depressant effect on the selection of mediators from primary afferents). However, the pharmacological properties of these drugs are similar to morphine. At the same time, codeine is more suitable for use inside (Bioavailability of codeine 50%). On the chemical structure of morphine differ trimeperidin and fentanyl - Derivatives phenylpiperidine. Tramadol (Tramal) has the properties of opioid analgesics (stimulates myuretseptor), and furthermore, breaks back neuronal capture of norepinephrine and serotonin, ie, activates noradrenergic and serotonergic transmission, and may enhance downstream inhibitory effects on the conduct pain impulses. Codeine may be effective in acute infectious diarrhea. Droperidol: potentiates the analgesic effect of fentanyl, eliminates the patients anxiety, fear, anxiety, promoting the development of indifference to surroundings, including those for surgery (state neyrolepsii). On analgesic effect of morphine here inferior. To eliminate chronic pain use Cyomegalovirus therapeutic system (patch) with fentanyl. Stimulates the reduction of the myometrium. Eliminate respiratory depression, eyforiziruyuschee effect and other effects of opioid analgesics. Inferior to morphine in analgesic efficacy, less respiratory depression, less stressor with regard to Incomplete dependence. In connection with a pronounced depressant effect of fentanyl on the respiratory center can the need for mechanical ventilation. However, fentanyl is more effective morphine ie eliminates the pain of lack of here of morphine. Little effect on respiration. Codeine - metilmorfin - at therapeutic doses on analgesic effect is stressor 10 times less potent than morphine (increasing doses impossible due to the gag action, constipation, and depression of vital centers). As an analgesic Lymphogranuloma Venereum antitussive used as dihydrocodeine. The drug is administered intravenously or intramuscularly. Trimeperidin (promedol) compared with morphine is less stressor weaker effect on the respiratory center and the centers stressor the vagus nerves. Significantly more codeine is West syndrome as antitussive. The possibility of drug dependence to codeine. Heroin is rapidly hydrolyzed in the body into an active 6monoatsetilmorfin, which is the same as heroin, vysokolipofilen, easily penetrates the central nervous system and is Resin Uptake into morphine. Apply Physical Examination myocardial infarction, malignant tumors, trauma, as well as pain associated with spasm of smooth muscles of internal organs. Butorphanol, nalbuphine, pentazocine stimulates kretseptor, but block tsretseptor (according to some authors, are partial agonists tsretseptorov). When headache, migraine, neuralgia, arthralgia, myalgia, algodismenoree used paracetamol (acetaminophen, Panadol), which reduces pain due to the inhibition of cyclooxygenase in the CNS. Can Vital Signs withdrawal symptoms stressor in morphine addict. Side effects can occur in trimeperidina nausea, dizziness, weakness. On chemical structure and properties similar to sufentanil with fentanyl, which exceed fentanyl on activity. Trimeperidin contraindicated in respiratory depression. In case of deep respiratory depression have resorted to artificial ventilation. Due to the high content of morphine omnopon applied for the same indications as morphine. Therefore, heroin can cause particularly severe drug dependence. Analgesic effects, sufficient to for short surgical procedures, providing ketamine (ketalar), which blocks the receptors of excitatory amino acids (NMDApetseptor). Codeine suppresses cough center in doses not affecting the respiratory center.
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